医療従事者の為の最新医療ニュースや様々な情報・ツールを提供する医療総合サイト

Wastewater Testing Labs Can Detect SARS-CoV-2 in Less Than Four Hours with New Methods

2021年08月16日 PM08:00
このエントリーをはてなブックマークに追加


 

MADISON, Wis.

A complete workflow developed by Promega Corporation enables wastewater testing laboratories, including public health organizations, to quickly assess the health of entire communities from a single sample. The Maxwell® RSC Enviro Total Nucleic Acid Kit and Wizard® Enviro Total Nucleic Acid Kit join a growing portfolio of products that support wastewater surveillance to monitor the spread of SARS-CoV-2.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20210816005009/en/

Wastewater-Based Epidemiology

Wastewater testing gained widespread popularity during the COVID-19 pandemic. Individuals infected with SARS-CoV-2 shed viral particles in their feces, even before they show symptoms. As a result, the levels of SARS-CoV-2 RNA in wastewater reflect the trends in infection rates in a given community. Collected consistently, this data can predict major outbreaks as much as seven days earlier than clinical tests.

“Wastewater gives you a snapshot of the entire community,” says Subhanjan Mondal, Senior Research Scientist at Promega Corporation. “To think of any other sample type that has that much wealth of information…it is hard to even imagine.”

Direct Capture Methods

Promega scientists recently published a study in Science of The Total Environment detailing direct capture methods for rapid and high-yield purification of viral nucleic acids from wastewater. These methods overcome the shortcomings of traditional precipitation-based isolation of viral particles, which fail to capture the degraded viruses present in wastewater. The publication demonstrates that direct capture methods produce samples that are compatible with RT-qPCR for monitoring infection levels and next-generation sequencing (NGS) for detecting viral variants.

Promega Workflow for Wastewater Surveillance

The methods published in Science of the Total Environment form the basis of the new Maxwell® RSC Enviro Total Nucleic Acid Kit, an automated method for purification of viral nucleic acids, as well as the manual Wizard® Enviro Total Nucleic Acid Kit. Both kits are designed to work with the large sample volumes required for wastewater testing and remove inhibitors that can disrupt downstream testing. The protocols can also be altered to process solids extracted from wastewater, in addition to only liquids.

The purification kits can be used with the SARS-CoV-2 RT-qPCR Kit for Wastewater to form a complete workflow for monitoring SARS-CoV-2 levels in wastewater. The workflow moves from sample to results in less than four hours, offering quick answers to inform decisions. This portfolio will continue to expand with additional amplification kits to be launched later.

Learn more about Promega solutions for wastewater-based epidemiology at www.promega.com/WastewaterMonitoring

About Promega Corporation

Promega Corporation is a leader in providing innovative solutions and technical support to the life sciences industry. The company’s portfolio of over 4,000 products support a range of life science work across areas such as cell biology; DNA, RNA and protein analysis; drug development; human identification and molecular diagnostics. For over 40 years these tools and technologies have grown in their application and are used today by scientists and technicians in labs for academic and government research, forensics, pharmaceuticals, clinical diagnostics and agricultural and environmental testing. Promega is headquartered in Madison, WI, USA with branches in 16 countries and over 50 global distributors. For more information, visit www.promega.com

View source version on businesswire.com: https://www.businesswire.com/news/home/20210816005009/en/

CONTACT

Penny Patterson

VP, Corporate Affairs

Promega Corporation

Phone: (608) 274-4330

E-mail: penny.patterson@promega.com

Related Posts Plugin for WordPress, Blogger...

同じカテゴリーの記事 

  • DKT International Implements Traditional and New Forms of Marketing in Africa, South America, and Southeast Asia to Expand Access to Contraceptives
  • オルガノンが計画外妊娠をめぐり世界規模の対話の喚起を目指す
  • IHMA Opens Microbiology Reference Laboratory in Shanghai, China to Further Support Global Anti-Infective Product Discovery and Development
  • Cyclica and IMPACT Therapeutics Team Up to Advance Differentiated Anti-cancer Drug Development
  • Takeda Selects Four New Partners for Annual Global Corporate Social Responsibility (CSR) Program to Help Strengthen Health Systems in Low- and Middle-Income Countries