医療従事者の為の最新医療ニュースや様々な情報・ツールを提供する医療総合サイト

SK Biopharmaceuticals and twoXAR Sign Collaboration Agreement to Discover and Develop First-In-Class Treatments for Non-Small Cell Lung Cancer

2019年04月18日 AM09:00
このエントリーをはてなブックマークに追加


 

PANGYO, South Korea & MOUNTAIN VIEW, Calif.

SK Biopharmaceuticals, a pharmaceutical company focused on disorders of central nervous system and cancer, and twoXAR, Inc., an artificial intelligence (AI)-driven biopharmaceutical company, today announced an agreement to discover and develop first-in-class therapeutics for non-small cell lung cancer (NSCLC).

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20190417005997/en/

Co-founder and CEO of twoXAR Andrew A. Radin (left) with Vice President of Cancer Research at SK Bio ...

Co-founder and CEO of twoXAR Andrew A. Radin (left) with Vice President of Cancer Research at SK Biopharmaceuticals Cheol-young Maeng (right) at R&D Collaboration Agreement signing ceremony at SK Biopharmaceuticals headquarters. (Photo: Business Wire)

Under the agreement, twoXAR will use its AI discovery technology to identify a set of initial candidates with the potential to treat lung cancer through novel biological mechanisms of action. After screening, SK Biopharmaceuticals plans to use its internal AI Drug Design technology to optimize a lead candidate and then conduct IND-enabling studies. SK Biopharmaceuticals will retain exclusive worldwide rights to develop and commercialize the drug candidate. twoXAR will receive an upfront payment and will be eligible for development and commercial milestone payments in addition to royalties.

Lung cancer is the leading cause of cancer deaths globally with a 5-year survival rate of less than 18%1. The two main types of lung cancer are small cell and non-small cell, accounting for 10-15% and 85% of all lung cancers, respectively. Treatment is based on the lung cancer stage and subtype, and generally consists of surgery, chemotherapy, radiation therapy, targeted therapy, or a combination of these treatments. However, the disease is known to become resistant to current lines of therapy. It is estimated that there were 2 million new lung cancer cases diagnosed worldwide in 20182.

“AI-powered approaches are pioneering new, more efficient ways to find promising new drug candidates and are enabling SK Biopharmaceuticals to build the next-generation pharmaceutical company,” said Cheol-Young Maeng, PhD, Vice President of Cancer Research at SK Biopharmaceuticals. “We are excited to combine twoXAR’s and SK Biopharmaceuticals’ technologies because of the potential to progress drug candidates from hypotheses to IND-enabling studies faster than ever before.”

“SK Biopharmaceuticals’ focus on powering end-to-end drug discovery and development by adopting new technologies to foster efficiencies makes them an ideal partner for twoXAR,” said Andrew A. Radin, Co-Founder and CEO of twoXAR. “As the leading cause of cancer death, lung cancer is a serious disease with high unmet need. We are pleased to be working with SK Biopharmaceuticals, who’s achieved remarkable success from discovery to filing for FDA approval, to combine our complementary platforms with a shared commitment to rapidly identify, validate, and develop novel treatments for lung cancer patients in need.”

About SK Biopharmaceuticals

SK Biopharmaceuticals is focused on research and development of treatments for disorders of central nervous system (CNS) and cancer.

Currently, SK Biopharmaceuticals is conducting research for the development of innovative new drugs at its research center in Pangyo, Gyeonggi Province, Korea. Further, the company is pursuing global clinical development and direct marketing through its U.S. subsidiary, SK Life Science, Inc., in Paramus, New Jersey, USA.

SK Biopharmaceuticals has a pipeline of eight compounds in development for the treatment of CNS disorders including epilepsy, sleep disorder and attention deficit hyperactivity disorder, among others. The first product the company is planning to commercialize, cenobamate (YKP3089), is an investigational compound for the potential treatment of partial-onset seizures in adult patients. The NDA for cenobamate for the potential treatment of partial-onset seizures in adult patients is currently under review by the FDA. For more information, visit SK Biopharmaceuticals’ website at www.skbp.com/eng.

About twoXAR

twoXAR is an artificial intelligence-driven biopharmaceutical company that leverages its computational platform to identify promising drug candidates, de-risk the opportunities through preclinical studies, and progress drug product candidates into the clinic through industry partnerships. Based in Mountain View, California, the twoXAR team includes experts in drug discovery and development, biomedical informatics, computational biology, data science and software development. Investors in twoXAR include SoftBank Ventures, the Andreessen Horowitz Bio Fund, OS Fund, CLI Ventures, and the Stanford-StartX Fund. For more information, please visit www.twoXAR.com.

1 American Lung Association website. Lung Cancer Fact Sheet. Accessed April 5, 2019 at https://www.lung.org/lung-health-and-diseases/lung-disease-lookup/lung-cancer/resource-library/lung-cancer-fact-sheet.html.

2 World Cancer Research Fund website. Lung Cancer Statistics. Accessed April 5, 2019 at https://www.wcrf.org/dietandcancer/cancer-trends/lung-cancer-statistics.

View source version on businesswire.com: https://www.businesswire.com/news/home/20190417005997/en/

CONTACT

For twoXAR
Andrew M. Radin
twoXAR, Inc.
aradin@twoxar.com
+1-650-382-2605

For SK Biopharmaceuticals
skbp_pr@naver.com

Related Posts Plugin for WordPress, Blogger...

同じカテゴリーの記事 

  • 印尼生命科学与技术学院在NCRM NICHE 2021上赢得第16届Fujio Cup Quiz大赛;印度Rajalakshmi工程学院获得亚军
  • 辉凌将在ACG 2021上展示基于微生物群的在研活体生物治疗药物RBX2660用于治疗艰难梭菌反复感染和IBD患者的获奖真实临床转归分析
  • ShouTi Secures $100 Million Series B Financing to Accelerate Development of Life-Changing Medicines Fueled by Advanced Computational, Structure-Based Drug Design Platform
  • 硕迪B轮成功融资1亿美元,利用先进的计算和结构药物设计平台加速开发改变患者命运的药物
  • CANbridge Pharmaceuticals CAN103 Investigational New Drug Application Approved in China for Treatment of Gaucher Disease