医療従事者の為の最新医療ニュースや様々な情報・ツールを提供する医療総合サイト

Harbour BioMed Announces Multi-Year Transgenic Platform Licensing Agreement with Celsius Therapeutics for Fully Human Monoclonal Antibody Drug Discovery

2018年06月01日 AM09:00
このエントリーをはてなブックマークに追加


 

SHANGHAI & ROTTERDAM, Netherlands &  CAMBRIDGE, Mass.

Harbour BioMed announced today that it has licensed its patented H2L2 fully human antibody discovery platform to Celsius Therapeutics, a newly launched company translating single-cell genomic insights into precision therapeutics. The license was issued through Harbour BioMed’s wholly owned subsidiary, Harbour Antibodies BV.

Harbour BioMed’s H2L2 transgenic mouse platform enables biotechnology, pharmaceutical companies, and academia to accelerate new drug development by generating fully human monoclonal antibodies. Under the licensing agreement, Celsius Therapeutics has rights to use the H2L2 platform for multiple programs over a multi-year period. Financial details were not disclosed.

“Therapeutic antibody discovery is one of the fastest growing segments of the global pharmaceutical research. More and more approved antibody drugs are fully human antibodies generated from transgenic platforms,” said Dr. Jingsong Wang, CEO of Harbour BioMed. “Harbour’s transgenic platforms, including H2L2 and HCAb for generating heavy chain only antibodies, have been widely used by over forty companies and academic centers. The platforms were engineered to produce high quality and highly diverse, full human antibodies through natural process of in vivo maturation from carefully selected human immunoglobulin transgenes. In the past twelve months, two of the antibodies generated from our H2L2 platform entered into human clinical trials.”

About Harbour BioMed
Harbour BioMed is a global biopharmaceutical company discovering and developing innovative therapeutics for oncology and immunological diseases. The company’s discovery and development programs are built around its two patented transgenic mouse platforms (Harbour Mice) for human antibody therapeutic discovery. The company is building its proprietary pipeline through its innovative internal discovery programs, and through in-licensing clinical stage assets that strategically fit its internal portfolio. Harbour BioMed also licenses the platforms to companies and academic institutions through its Harbour Antibodies subsidiary. For additional information, please visit http://www.harbourbiomed.com.

About Harbour Mice
A fully owned subsidiary of Harbour BioMed, Harbour Antibodies owns two strains of transgenic mice for generating human therapeutic antibodies: (1) mice that generate antibodies comprised of two heavy chains and two light chains (H2L2) with fully human variable regions; and (2) mice that generate novel “heavy chain only” antibodies (HCAb). The HCAb mice enable the development of antibody fragment-based therapeutics such as nanobodies, bi-specific antibodies and CAR-T with favorable biophysical properties. For additional information, please visit http://harbourantibodies.com.

View source version on businesswire.com: https://www.businesswire.com/news/home/20180531005150/en/

CONTACT

Harbour Antibodies
Timothy Miller
timothy.miller@harbourbiomed.com
or
Harbour
BioMed
Xian Wu
xian.wu@harbourbiomed.com

Related Posts Plugin for WordPress, Blogger...
 

同じカテゴリーの記事 

  • CANbridge Life Sciences Receives Approval to Commence CAN017 Ib/III Trial in Esophageal Squamous Cell Cancer (ESCC) In China
  • AVEO Announces Acceptance of CANbridge Investigational New Drug Application for CAN017 (AV-203) Trial in Esophageal Squamous Cell Cancer (ESCC) in China
  • STAAR Surgical and Shinjuku LASIK Clinic in Japan Announce Strategic Cooperation Agreement
  • 新研究调查诊断性多通道睡眠检查之前采用Masimo SET®脉搏氧饱和度仪居家监测筛查唐氏综合征患儿罹患阻塞性睡眠呼吸暂停的风险
  • ダウン症候群の小児を対象とする睡眠時障害診断のマルチチャンネル研究に先立つ閉塞性睡眠時無呼吸症リスクのスクリーニングとしてMasimo SET®パルスオキシメトリーを使用するホームモニタリングの有用性を検討する新研究